Established in 2001,
the School of Medicine at Swansea University is a centre of excellence in world-class research and medical education. In January 2005, it was announced that work would
begin on the Institute of Life Sciences, a development that would make Swansea University a world leader in medical research.
The Institute of Life
Sciences will not only benefit from some of the finest minds in medical research, but also from the European Deep Computing Visualisation Centre for Medical Applications. The result of a collaboration
agreement between Swansea University and IBM, the Centre will include a new IBM supercomputer. The computer - named Blue C - is one of the fastest computers in the world dedicated to life
sciences research and will significantly accelerate the programmes of the Institute.
Julian Hopkin, Professor of Medicine and Director of the School of Medicine, spoke to Sali Earls about the project.
How does the relationship with IBM work? Are they developing solutions specifically for the School of Medicine in Swansea?
IBM and the School of Medicine act as collaborators, as defined in our research and development contract. Each party brings its own particular expertise into the collaboration thus enhancing the
power of the work, and delivering practical solutions for medicine and health. IBM is contributing computing power and associated computing expertise whilst the School of Medicine is contributing
biomedical and health/clinical research techniques.
The key areas of collaborative working are in new methods of medical visualisation, informatics applied to the delivery of health, and informatics applied to the solution of molecular structures, which
is key to novel diagnostics and therapeutics.
Why did you choose to work with IBM over any other solutions provider?
The School chose to work with IBM firstly because of its computing and infrastructure capabilities, which were relevant to strengthening vital research areas in biomedicine and health. Secondly we
were aware that IBM had an intrinsic interest in biomedicine and health technologies, with a commitment to find solutions, and this was key for us.
You mention that you have worked closely with other departments, could you go into some detail about these relationships?
The whole ethos of the new Institute of Life Science is that it will conduct medical research in an interdisciplinary way. This means that the medical research capability of the School (led by 22
professors) will be strongly complemented by science from other schools on the University campus. This also greatly increases our research power and capability and promises new solutions to old
problems.
Some key examples are the involvement of engineering and physics at the University and the application of nanotechnology to medicine. These nanotechnology methods improve our research
power. They also have real potential in delivering revolutionary techniques into medicine with small devices that can be used to monitor biological processes in the body, or to release medications in
the right place in the body, and at the right time.
Another example is the involvement of computing at the University, with virtual reality techniques, and the Department of Radiology at the hospital Trust. Here the potential is in forward-looking
medical visualisation.

Could you tell me something about what these new technologies can do, and what the ability to visualise means for the School of Medicine
and also for the medical profession?
The revolutionary new modes of medical visualisation can operate at least at two levels.
Firstly, at the macro level, we have a great interest in creating 3-D images of the body and particular organs, and extending this into virtual reality. This promises the most detailed views of human
anatomy in the healthy and diseased state, and will allow for more accurate diagnostics and more targeted therapeutics. Additionally this promises great value - in 3D images but also in virtual reality - for
training medical students and further training hospital doctors in specialised techniques.
At a second level, the visualisation can be at the molecular level. Solving the 3-D structures of molecules playing a key part in a disease will allow ultimately for "designer" drugs to fit these
molecular disease targets and knock them out. This promises advances in therapeutics.
So once the project is underway, what do you feel is the next step technologically? I know that the objective is for this to lead to spinout companies, but how do you feel this is going to
move forward?
Our work in these areas, and in the collaboration between the School and IBM at the Institute, has already started. A further key feature of the Institute's operation will be the early engagement of other
commercial partners at the start of research projects. Through this we hope our research plans will be refined and efficient and lead to practical products, applicable to medicine and health, at the first
possible opportunity. We cannot say when the first product will emerge, but the enterprise is underway.
The Institute of Life Sciences will open its doors in December 2006. Visit www.medicine.swan.ac.uk to find out more about the
School of Medicine at Swansea University, and the plans for the Institute as they take shape.